[Skip to content]

Enter search here...
Worcestershire Acute Hospitals NHS Trust
.
.
Test
G-1-P Screen (Galactose-1-Phosphate Uridyl Transferase)
CategoryClinical Biochemistry
Code
G1PU
Test information
PLEASE SEND SAMPLE MON - THURS, as needs to be received by referral laboratory within 24 hours of collection. If required urgently please contact the laboratory prior to sending. 
Used in the diagnosis of Classical Galactosaemia:  Lactose (glucose-galactose) is cleaved in the gut and the galactose absorbed.  G1PUT is one enzyme in the pathway that converts galactose to glycogen. Deficiency causes increased levels of galactose-1phosphate and galactitol which causes cataracts on its accumulation. Urine reducing substances should be positive If high suspicion index, place baby onto a galactose/lactose restricted diet until results back
Pre-analytical
If transfused measure Galactose-1-phosphate (Li Hep whole blood) or do GPUT on mother.
Reference range
see report
Special requirements
WHOLE BLOOD or BLOOD SPOT
Tube type
Li Hep whole blood
Green top tube
Minimum volume
0.5 mL
TAT Inpatient
4 weeks
TAT GP/Outpatient
4 weeks
Referral lab
Depts of Blood Sciences and Metabolic Biochemistry, Birmingham Children's Hospital
Page last updated: 11 January 2022