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Worcestershire Acute Hospitals NHS Trust
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Test
Gabapentin
CategoryClinical Biochemistry
Code
GABA
Test information
Anticonvulsant drug. TDM is useful when non-compliance or toxicity is suspected Approx time to steady state 1-2 days. Target 2-20mg/L. Absorption of gabapentin is very rapid with peak conc at 2-3h. Elimination half life 5-7h, necessitates dosing 3 times daily. Drug is eliminated entirely via kidneys as unchanged compound. CNS adverse effects are similar to other anticonvulsant drugs
Pre-analytical
Samples should be taken pre-dose (trough)
Reference range
2-20 mg/L
Special requirements
Plasma or serum
Tube type
Li Hep/ EDTA/ SST
Green, purple and gold tops
Minimum volume
200 uL
TAT Inpatient
4 weeks
TAT GP/Outpatient
4 weeks
Referral lab
Regional Toxicology Laboratory, City Hospital
Page last updated: 11 January 2022